Nutrition and supplement support
Protect food intake as appetite changes
When food becomes less appealing, set up small meals that still provide protein, energy and variety. A yoghurt with fruit, eggs with toast, tofu with rice or fish with potatoes may be more manageable than one large meal. The goal is adequate nourishment, not the longest possible period without hunger.
Strength matters alongside weight
Resistance exercise and sufficient protein help support muscle during weight reduction. Record functional changes such as walking tolerance or usual training performance. If these deteriorate while weight falls quickly, review food intake and treatment rather than celebrating the scale alone.
Supplements with a specific purpose
A protein supplement can fill a practical food gap. Vitamin D, B12, iron or calcium should be considered according to diet, risk factors and testing. There is no demonstrated retatrutide-specific vitamin stack. Iron may aggravate constipation, and large magnesium doses can worsen diarrhoea.
Hydration and stimulants
Vomiting and diarrhoea can cause fluid loss. Ongoing symptoms need assessment, especially with kidney disease. Avoid using high-caffeine “fat burners” to compensate for fatigue; they can complicate heart-rate symptoms and conceal under-eating. Electrolytes are not a substitute for medical attention when fluids cannot be retained.