Identity
Humanin is a short peptide identified through experiments on neuronal survival.
Cultured neuronal models exposed to Alzheimer-related insults.
Peptide library
Humanin
Your guide to this compound.
Mechanism illustrationEnlarge
Evidence in perspective
The founding experiments concern neuronal survival in laboratory models. Donor-cell origin does not create human treatment evidence. An indexed correction to the early paper still needs its exact content reconciled before a full source appraisal can close.
About this assessment
Existing source snapshot critically reassessed.
Based on the selected source scope described in this profile, often an indexed abstract. Full methods and clinician sign-off remain pending; no systematic-review claim.
Editorial assessment · 2026-09-07
Who was studied
Cultured neuronal models exposed to Alzheimer-related insults.
What the sources found
The original study reported reduced cell death in selected experimental models; it was not a dementia treatment trial.
Cultured neuronal models exposed to Alzheimer-related insults.
Regulatory scope
No jurisdiction-specific marketing authorization has been verified in this snapshot; study publication is not regulatory approval.
What remains unknown
These findings do not establish human efficacy, long-term safety, or equivalence to products sold under this name. This is a focused source snapshot, not an exhaustive clinical review.
How it works
Humanin is a short peptide identified through experiments on neuronal survival.
Read the study-specific findings and limitations in Medical. Mechanistic activity does not establish a treatment benefit.
Preclinical research
The catalog primarily cites laboratory or animal research. Human benefit, a safe dose and long-term risks cannot be inferred from those findings.
Reported adverse effects
- The cited evidence does not establish comprehensive human adverse-event rates.
Contraindications
- A complete clinical contraindication profile has not been established in this review.
Preclinical research
The catalog primarily cites laboratory or animal research. Human benefit, a safe dose and long-term risks cannot be inferred from those findings.
Sources used for this snapshot
Claim-by-claim evidence
Findings
The original study reported reduced cell death in selected experimental models; it was not a dementia treatment trial.
Cultured neuronal models exposed to Alzheimer-related insults.
References
Hashimoto et al. A rescue factor abolishing neuronal cell death. PNAS. 2001.
PMID: 11371646
Humanin in human cerebrovascular smooth muscle cell cultures. 2003.
PMID: 12558989
Catalog review date: Sep 6, 2026. This date alone does not establish independent clinical review.