Identity
5-Amino-1MQ is an experimental small-molecule NNMT inhibitor, not a peptide.
Cell studies and high-fat-diet obese mice.
Peptide library
5-Amino-1MQ
Your guide to this compound.
Mechanism illustrationEnlarge
Evidence in perspective
Mouse adiposity and enzyme inhibition are early biological signals. They cannot establish a human weight-loss effect, safe systemic exposure or a clinical supplement combination.
About this assessment
Existing source snapshot critically reassessed.
Based on the selected source scope described in this profile, often an indexed abstract. Full methods and clinician sign-off remain pending; no systematic-review claim.
Editorial assessment · 2026-09-07
Who was studied
Cell studies and high-fat-diet obese mice.
What the sources found
NNMT-inhibitor experiments reported changes in mouse adiposity; they do not establish safe or effective human treatment.
Cell studies and high-fat-diet obese mice.
Regulatory scope
No jurisdiction-specific marketing authorization has been verified in this snapshot; study publication is not regulatory approval.
What remains unknown
These findings do not establish human efficacy, long-term safety, or equivalence to products sold under this name. This is a focused source snapshot, not an exhaustive clinical review.
How it works
5-Amino-1MQ is an experimental small-molecule NNMT inhibitor, not a peptide.
Read the study-specific findings and limitations in Medical. Mechanistic activity does not establish a treatment benefit.
Preclinical research
The catalog primarily cites laboratory or animal research. Human benefit, a safe dose and long-term risks cannot be inferred from those findings.
Reported adverse effects
- The cited evidence does not establish comprehensive human adverse-event rates.
Contraindications
- A complete clinical contraindication profile has not been established in this review.
Preclinical research
The catalog primarily cites laboratory or animal research. Human benefit, a safe dose and long-term risks cannot be inferred from those findings.
Sources used for this snapshot
Claim-by-claim evidence
Findings
NNMT-inhibitor experiments reported changes in mouse adiposity; they do not establish safe or effective human treatment.
Cell studies and high-fat-diet obese mice.
References
Neelakantan et al. Selective NNMT inhibitors in high-fat-diet-induced obesity in mice. 2018.
PMID: 29155147
Catalog review date: Sep 6, 2026. This date alone does not establish independent clinical review.